Drontal Plus XL Womer Tablets

Bayer Heathcare Drontal Plus XL Womer Tablets

Product Description

To ensure that you read the most up to date product information link to  http://www.vmd.defra.gov.uk/ProductInformationDatabase/Search.aspx

Link to Veterinary Medicines Suspected Adverse Reaction Scheme

                                            Data Sheet Information

 
Presentation
 
Drontal Plus XL Flavour Tablets are pale brown to brown oval-shaped divisible tablets scored on both sides containing 175 mg praziquantel, 504 mg pyrantel embonate and 525 mg febantel as active constituents and 408.0 mg Artificial beef flavour irradiated.
 
 
.
 
 
 
 
 
 
 
  
 

Dosage

For oral administration only.

The recommended dose rate is: 15 mg/kg body weight febantel, 14.4 mg/kg pyrantel and 5 mg/kg praziquantel.
This is equivalent to 1 Drontal Plus XL Flavour Tablet per 35 kg bodyweight as follows:
Dosage Guide
Drontal Plus XL Flavour Tablets
17.5 kg body weight = ½ tablet
>17.5 - 35 kg body weight = 1 tablet
>35 - 52.5 kg body weight = 1½ tablets
>52.5 - 70 kg body weight = 2 tablets
Drontal Dog Tasty Bone Tablets should be used to achieve accurate dosing in dogs weighing less than 17.5 kg. The dose is equivalent to 1 tablet per 10 kg.

Administration

Oral administration: the tablet(s) can be given directly to the dog or disguised in food. No starvation is needed before or after treatement.
For routine treatment a single dose is recommended.
For the control of Toxocara, nursing bitches should be dosed 2 weeks after giving birth and every two weeks until weaning.
For routine control adult dogs should be treated every 3 months. In the event of heavy roundworm infection a repeat dose should be given after 14 days.

Further Information

Further information
 
Pharmacotherapeutic group: Anthelmintics, tetrahydropyrimidine. ATC VetCode: QP52AF30.
The product contains three active substances active against roundworms and tapeworms: 1. Febantel, a probenzimidazole, 2. Pyrantel embonate (pamoate) a tetrahydropyrimidine derivative, 3. Praziquantel, a partially hydrogenated pyrazinoisoquinoline derivative.
In this fixed combination product pyrantel and febantel act synergistically against relevant nematodes (ascarids, hookworms and whipworms) in dogs. In particular, the activity spectrum covers Toxocara canis, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma caninum and Trichuris vulpis.
The spectrum of activity of praziquantel covers all important cestode species in dogs, in particular all Taeniaspp, Dipylidium caninum, Echinococcus granulosus and Echinococcus multilocularis. Praziquantel acts against adult and immature forms of these parasites.
Praziquantel is very rapidly absorbed and distributed throughout the parasite. Both in vivo and in vitro studies have shown that praziquantel causes severe damage to the parasite integument, resulting in contraction and paralysis. There is an almost instantaneous tetanic contraction of the parasite musculature and a rapid vacuolisation of the syncytial tegument. This rapid contraction has been explained by changes in divalent cation fluxes, especially calcium.
Pyrantel acts as a cholinergic agonist. Its mode of action is to stimulate nicotinic cholinergic receptors of the parasite, induce spastic paralysis and thereby allow removal from the gastrointestinal (GI) system by peristalsis.
Within the mammalian system febantel undergoes ring closure forming fenbendazole and oxfendazole. It is these chemical entities which exert the anthelmintic effect by inhibition of tubulin polymerisation. Formation of microtubules is thereby prevented, resulting in disruption to structures vital to the normal functioning of the helminth. Glucose uptake, in particular, is affected, leading to a depletion in cell ATP. The parasite dies upon exhaustion of its energy reserves, which occurs 2-3 days later.
 
Marketing authorisation number
Vm 00010/4153.

Precautions/Warnings

Consult a veterinary surgeon before treating pregnant animals for roundworms.
The product may be used during lactation.
Do not exceed the recommended dose when treating pregnant bitches.
 
 
 
Do not use simultaneously with piperazine compounds.
Concurrent use with other cholinergic compounds is not recommended.
The product is well tolerated in dogs. In safety studies doses of 5 x or greater gave rise to occasional vomiting.
Fleas serve as intermediate hosts for one common type of tapeworm - Dipylidium caninum. Tapeworm infestation is certain to re-occur unless control of intermediate hosts such as fleas, mice etc. is undertaken.
Since it contains praziquantel, the product is effective against Echinococcus multilocularis, which does not occur in the UK or Ireland but is becoming more common in some European countries. As a precautionary measure to prevent establishment of E. multilocularis in the UK and Ireland, it is recommended that all dogs entering the country be treated with praziquantel
User safety
In case of accidental ingestion, seek medical advice and show package leaflet to the physician.
In the interests of good hygiene, persons administering the tablets directly to the dog, or by adding them to the dog's food, should wash their hands afterwards.
Environmental safety
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
 
Pharmaceutical precautions
 
Do not store above 25°C.
Any part-used tablets should be discarded.
Shelf-life of the veterinary medicinal product as packaged for sale: 3 years

Drontal Plus XL Wormer Tablets

2 Tablet Pack

You will be required to submit a POM-VPS form with this product at the checkout to enable completion of your order.

0
Write the first review

in stock In stock

£19.50

up down
Drop a hint
Home Delivery

UK mainland delivery from £4.50